Gas transfer (TLCO)
What this test measures
TLCO measures how well gas crosses from the air sacs into the blood, using a tiny amount of carbon monoxide. It reflects the lung's working surface and its blood supply.
Why doctors request it
Used in lung fibrosis, emphysema, some heart conditions and before some treatments that can affect the lungs.
What commonly pushes it up
- Asthma, sometimes
- Bleeding into the lungs
- Lying flat, and a high haemoglobin
What commonly pushes it down
- Emphysema
- Lung fibrosis
- Lung clots and other circulation problems in the lung
- Anaemia, which the lab corrects for
- Smoking on the day
Everyday reasons for a value outside the range
- Anaemia lowers it, so a haemoglobin-corrected value is often printed
- Smoking within hours lowers it
- Predicted values depend on age, sex and height
About the sample
No smoking for 24 hours beforehand where possible.
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Read my report freeThis is an educational summary of results you uploaded. It is not medical advice, a diagnosis or a treatment plan, and it does not replace the doctor who requested the test. If you are worried, or a result is marked outside range, discuss it with your doctor. Written and reviewed by a UK consultant physician. Reference ranges vary between laboratories.