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Sirolimus

Medicine levels · also printed as Sirolimus level, Rapamycin, Rapamune level, Sirolimus trough

Typical UK adult range4 to 12 ug/L

Target ranges are set by the treating team and printed by the lab; the printed range applies.

What this test measures

Sirolimus is an anti-rejection medicine used in some transplant regimens and in a few rare conditions. Its level is measured because it clears slowly and interacts with many medicines.

Why doctors request it

Measured by transplant clinics, less often than tacrolimus because it changes slowly.

What commonly pushes it up

Some medicines as a class that slow its breakdown
Liver disease

What commonly pushes it down

Missed tablets
Some medicines as a class that speed its breakdown

Everyday reasons for a value outside the range

It takes a week or more to settle after any change

About the sample

Just before the daily tablet.

Written by a UK consultant physician. Typical UK adult reference ranges; your laboratory's own printed range takes precedence.

Got a report with Sirolimus on it?

Upload a photo or PDF and see every line against the range your lab printed, explained in plain English. First report free.

Read my report free

This is an educational summary of results you uploaded. It is not medical advice, a diagnosis or a treatment plan, and it does not replace the doctor who requested the test. If you are worried, or a result is marked outside range, discuss it with your doctor. Written and reviewed by a UK consultant physician. Reference ranges vary between laboratories.