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Free to total PSA ratio

Tumour markers · also printed as Free/total PSA, F/T PSA, PSA ratio, Free:total PSA, %free PSA

Typical UK adult range25 % and above

Ranges vary between laboratories; the range printed on the report takes precedence.

What this test measures

This ratio expresses free PSA as a percentage of total PSA. A higher percentage of free PSA is generally the more reassuring direction in the general population.

Why doctors request it

Used by specialists to help decide whether further tests are needed when the total PSA is in a grey zone.

What commonly pushes it up

A larger, benign prostate tends to raise the ratio

What commonly pushes it down

Prostate cancer tends to lower it, but there is much overlap

Everyday reasons for a value outside the range

Printed either as a percentage or as a decimal fraction
Only meaningful in the total PSA range the lab specifies

About the sample

Same preparation as total PSA.

Written by a UK consultant physician. Typical UK adult reference ranges; your laboratory's own printed range takes precedence.

Got a report with Free to total PSA ratio on it?

Upload a photo or PDF and see every line against the range your lab printed, explained in plain English. First report free.

Read my report free

This is an educational summary of results you uploaded. It is not medical advice, a diagnosis or a treatment plan, and it does not replace the doctor who requested the test. If you are worried, or a result is marked outside range, discuss it with your doctor. Written and reviewed by a UK consultant physician. Reference ranges vary between laboratories.